Sibutramine For Sale Online
Structurally, sibutramine is similar to the class of amphetamines, although it does not possess their biological properties. Sibutramine, a central action drug, is a reuptake inhibitor of serotonin (53%), norepinephrine (54%) and dopamine (16%), which increases the level of these mediators in the intersynaptic space. Thus, increasing the concentration of serotonin in the center of hunger and saturation, the drug suppresses the appetite.
Sibutramine may cause a change (improve) mood, because the control of energy homeostasis and mood often used the overlapping parts of the brain (eg, serotonergic).
Doses of Sibutramine and a way of using
The average dose of Sibutramine is 10 mg once a day in the first half of the day, if it is not enough after a few days of use, the dose can be raised to 15 mg per day. Usually, 6 months after the start of treatment and until the drug is stopped, appetite normalizes, and body weight is set on a plateau. Do not exceed the dose, because often this is associated with side effects and complications. Admission is carried out in combination with a low-calorie diet and exercise. After discontinuation of the drug is often observed a set of lost weight. Sibutramine is an effective means of reducing body weight and food intake during treatment for a short period of time (6-12 months), its effectiveness decreases with prolonged intake of the drug (> 1 year).
Sibutramine in the US
In the US, it is classified as a means of causing dependence, although it is not. The only reason for the control is abuse as an anorexic, getting it for the first time under the prescription of a doctor, people then begin to continue unauthorized reception for weight loss themselves.
Side effects of Sibutramine
Relatively often there are side effects from the cardiovascular system (about 10%): an increase in blood pressure by 2-20 mm Hg, an increase in the heart rate by 3-20 beats / min. In 2010, the FDA expressed concern about the high risk of heart disease and strokes with Sibutramine in people with cardiovascular disease. There are also side effects associated with its noradrenergic stimulation of the hypothalamus of the mechanisms regulating appetite and sympathomimetic properties: dry mouth, nausea, taste change, digestive disorders, constipation, insomnia, anxiety, algomenorrhea, pain in muscles and joints, difficulty urinating, violation view.
At a young age, in the absence of heart disease and blood vessels, Sibutramine is considered a safe drug. If side effects occur, after withdrawal all symptomatology disappears without harm to health. Serious complications are rare.
Scientists believe that a person is at greater risk of being obese than with Sibutramine.